Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.40 |
| ▸ | AR | P10275 | 10/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13372548 | 1.00 | PGR (0.40) | PGRARCYP19A1NR3C1PDE4D | |
| SCHEMBL13372687 | 0.89 | PGR (0.40) | PGRARCYP19A1NR3C1PDE4D | |
| SCHEMBL13372639 | 0.89 | PGR (0.40) | PGRARCYP19A1NR3C1PDE4D | |
| SCHEMBL922896 | 0.89 | PGR (0.39) | PGRARCYP19A1NR3C1PDE4D | |
| SCHEMBL924476 | 0.89 | PGR (0.39) | PGRARCYP19A1NR3C1PDE4D | |
| SCHEMBL13372575 | 0.88 | PGR (0.36) | PGRARCYP19A1NR3C1LMNA | |
| SCHEMBL13372573 | 0.88 | PGR (0.36) | PGRARCYP19A1NR3C1LMNA | |
| SCHEMBL13372623 | 0.83 | PGR (0.58) | PGRARCYP19A1NR3C1LMNA | |
| SCHEMBL13372624 | 0.83 | PGR (0.58) | PGRARCYP19A1NR3C1LMNA | |
| SCHEMBL13372652 | 0.81 | PGR (0.60) | PGRARNR3C1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | claimed |
| EP-2238150-B1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID y-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |