Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952354 | 0.84 | MAPT (0.37) | ABL1MAPTALDH1A1MAPK1KDM5B | |
| SCHEMBL5952661 | 0.82 | ABL1 (0.35) | ABL1KDM5B | |
| SCHEMBL13375334 | 0.82 | ABL1 (0.34) | ABL1 | |
| SCHEMBL13375330 | 0.82 | ABL1 (0.34) | ABL1KDM5B | |
| SCHEMBL5952646 | 0.82 | ABL1 (0.33) | ABL1KDM5B | |
| SCHEMBL5952614 | 0.79 | MAPT (0.34) | ABL1MAPTALDH1A1KDM5BNPC1 | |
| SCHEMBL13373566 | 0.78 | SYK (0.35) | ABL1MAPTALDH1A1KDM5BLMNA | |
| SCHEMBL3934079 | 0.77 | FGFR1 (0.45) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL5578155 | 0.76 | KMT2A (0.42) | MAPTALDH1A1 | |
| SCHEMBL3926150 | 0.76 | MAPT (0.41) | ABL1MAPTALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |