Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13375330 | 0.90 | ABL1 (0.34) | ABL1 | |
| SCHEMBL13375054 | 0.85 | ABL1 (0.33) | ABL1CYP4F2CYP4A11 | |
| SCHEMBL13373566 | 0.84 | SYK (0.35) | ABL1 | |
| SCHEMBL13375210 | 0.82 | ABL1 (0.35) | ABL1 | |
| SCHEMBL3928294 | 0.82 | EGFR (0.37) | ABL1 | |
| SCHEMBL5952646 | 0.82 | ABL1 (0.33) | ABL1 | |
| SCHEMBL13375327 | 0.82 | ABL1 (0.37) | ABL1 | |
| SCHEMBL3926150 | 0.82 | MAPT (0.41) | ABL1 | |
| SCHEMBL3929262 | 0.81 | MAPT (0.36) | ABL1 | |
| SCHEMBL13375196 | 0.81 | ABL1 (0.37) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |