Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | NAAA | Q02083 | 2/20 | 0.66 |
| ▸ | PLK1 | P53350 | 2/20 | 0.62 |
| ▸ | MLYCD | O95822 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13375750 | 0.98 | L3MBTL1 (0.71) | L3MBTL1NAAAPLK1MLYCDTMEM97 | |
| SCHEMBL10950073 | 0.95 | PLK1 (0.64) | L3MBTL1NAAAPLK1MLYCDTMEM97 | |
| SCHEMBL9784422 | 0.92 | L3MBTL1 (0.71) | L3MBTL1NAAAPLK1MLYCDTMEM97 | |
| SCHEMBL9491031 | 0.92 | L3MBTL1 (0.71) | L3MBTL1NAAAPLK1MLYCDTMEM97 | |
| SCHEMBL10949132 | 0.88 | PLK1 (0.70) | L3MBTL1NAAAPLK1MLYCDTMEM97 | |
| SCHEMBL15166526 | 0.88 | L3MBTL1 (0.71) | L3MBTL1NAAAPLK1MLYCDCA2 | |
| SCHEMBL10950404 | 0.88 | PLK1 (0.68) | PLK1TMEM97SIGMAR1CA2MEN1 | |
| SCHEMBL6535660 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDCA2HDAC3 | |
| SCHEMBL9265536 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDCA2HDAC3 | |
| SCHEMBL845966 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAAMLYCDCA2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288339-B2 | GLP-1 compounds | AMGEN INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-20100048468-A1 | GLP-1 COMPOUNDS | AMGEN INC. (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048468-A1 | GLP-1 COMPOUNDS | GLP1R, IAPP, GIPR | L3MBTL1 1069/4885NAAA 789/4885PLK1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.