Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11960956 | 0.83 | NR3C1 (0.67) | NR3C1 | |
| SCHEMBL10116140 | 0.83 | NR3C1 (0.76) | NR3C1 | |
| SCHEMBL10115890 | 0.82 | NR3C1 (0.74) | NR3C1 | |
| SCHEMBL10115261 | 0.81 | NR3C1 (0.78) | NR3C1 | |
| SCHEMBL11960685 | 0.81 | NR3C1 (0.78) | NR3C1 | |
| SCHEMBL14218160 | 0.81 | NR3C1 (0.75) | NR3C1 | |
| SCHEMBL10115402 | 0.81 | NR3C1 (0.75) | NR3C1 | |
| SCHEMBL14198056 | 0.81 | NR3C1 (0.78) | NR3C1 | |
| SCHEMBL10115129 | 0.81 | NR3C1 (0.78) | NR3C1 | |
| SCHEMBL11995476 | 0.81 | NR3C1 (0.68) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599201-B1 | SELECTIVE NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-04-14 | — | — | EP | disclosed |
| US-7411073-B2 | Selective non-steroidal glucocorticoid receptor modulators | MERCK & CO., INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7411073-B2 | Selective non-steroidal glucocorticoid receptor modulators | MERCK & CO., INC. (US) | 2008-08-12 | — | — | US | disclosed |