Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.97 |
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095609 | 1.00 | KMT2A (0.97) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL31323430 | 0.94 | KMT2A (0.86) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL6199902 | 0.92 | KMT2A (0.82) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL15307911 | 0.91 | MEN1 (0.81) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL22014628 | 0.90 | MEN1 (0.80) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL27604377 | 0.89 | MEN1 (0.78) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL3970912 | 0.88 | MEN1 (0.76) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL4814264 | 0.88 | MEN1 (0.76) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL7393652 | 0.88 | MEN1 (0.76) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL379160 | 0.88 | MEN1 (0.76) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658789-B2 | Method for preparing linezolid and intermediates thereof | LIANHE CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2014-02-25 | — | — | US | disclosed |
| EP-2388251-B1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | LIANHE CHEMICAL TECHNOLOGY CO LTD (CN) | 2013-08-28 | — | — | EP | disclosed |
| EP-2388251-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | Lianhe Chemical Technology Co., Ltd. (CN) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275805-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | LIANHE CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2011-11-10 | — | — | US | disclosed |
| US-8038543-B2 | Golf swing training device | CAPESIUS DEAN C | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275805-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | HDAC9, KAT5, ACMSD | KMT2A 158/4885MEN1 3608/4885NPSR1 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.