Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18475321 | 0.75 | HSD17B10 (0.39) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL28345389 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL3543457 | 0.74 | TSHR (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL17772680 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL3447171 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL9410541 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL29455598 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL6137109 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL170140 | 0.74 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29709689 | 0.72 | MAPK1 (0.55) | MAPK1TSHRHPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2021124172-A1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2021-06-24 | — | — | WO | disclosed |
| US-9796640-B2 | Method for producing optically active carboxylic acid ester | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2017-10-24 | — | — | US | disclosed |
| EP-2809668-B1 | 4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-04-12 | — | — | EP | disclosed |
| EP-1797073-B1 | BICYCLIC ANILIDE SPIROLACTAM CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2007061696-A2 | SPIROLACTAM BICYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2007-05-31 | — | — | WO | disclosed |