Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057018 | 0.75 | KDM4E (0.43) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL11148469 | 0.75 | FEN1 (0.50) | MAPK1HPGDTSHRUSP2ALDH1A1 | |
| SCHEMBL170140 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL6137109 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL28345389 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL3543457 | 0.74 | TSHR (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL3447171 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL9410541 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL13378055 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 | |
| SCHEMBL29455598 | 0.74 | MAPK1 (0.57) | MAPK1HPGDTSHRUSP2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079502-A1 | METAL CHELATING COMPOUNDS FOR USE IN TREATING DISEASES | UNIVERSITY OF NORTHUMBRIA (GB) | 2016-05-26 | — | — | WO | disclosed |