Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380128 | 0.95 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP2D6 | |
| SCHEMBL13380159 | 0.93 | CYP2C19 (0.69) | SMN1; SMN2ALDH1A1KDM4ECYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL5010675 | 0.83 | HTT (0.72) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP2D6 | |
| SCHEMBL1382764 | 0.81 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL5010632 | 0.81 | CACNA1G (0.72) | SMN1; SMN2ALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL5013746 | 0.80 | HTT (0.59) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP2D6 | |
| SCHEMBL8150783 | 0.80 | CD274 (0.85) | SMN1; SMN2ALDH1A1KDM4ETSHRNAMPT | |
| Hydrochloric Acid SCHEMBL5010944 | 0.79 | CACNA1G (0.74) | SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5010940 | 0.79 | CACNA1G (0.74) | SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5013756 | 0.79 | CACNA1G (0.74) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177902-A1 | Method and system for multi-stage isoelectric focussing | Picosep A/S (DK) | 2010-04-21 | — | — | EP | disclosed |