Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.41 |
| ▸ | VCP | P55072 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206165 | 0.93 | EGFR (0.48) | EGFRSUV39H2VCPDPP4ALDH1A1 | |
| SCHEMBL23259863 | 0.87 | CARM1 (0.45) | EGFRSUV39H2VCPDPP4ALDH1A1 | |
| SCHEMBL13380517 | 0.87 | DPP4 (0.39) | EGFRSUV39H2VCPDPP4ALDH1A1 | |
| SCHEMBL517488 | 0.86 | EGFR (0.48) | EGFRSUV39H2VCPDPP4ALDH1A1 | |
| SCHEMBL13380460 | 0.80 | SUV39H2 (0.44) | EGFRSUV39H2DPP4ALDH1A1SSTR5 | |
| SCHEMBL10205917 | 0.79 | DPP4 (0.37) | EGFRVCPDPP4ALDH1A1SSTR5 | |
| SCHEMBL10206184 | 0.78 | DPP4 (0.39) | SUV39H2DPP4ALDH1A1HTR4LGMN | |
| SCHEMBL1911920 | 0.78 | DPP4 (0.40) | DPP4ALDH1A1LGMNMAPT | |
| SCHEMBL2362547 | 0.77 | DPP4 (0.46) | SUV39H2DPP4SSTR5LGMN | |
| SCHEMBL17265199 | 0.77 | ALDH1A1 (0.46) | DPP4ALDH1A1GAALGMNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172461-A1 | DI(ARYLAMINO)ARYL COMPOUND | Astellas Pharma Inc. (JP) | 2010-04-07 | — | — | EP | disclosed |