Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.64 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.64 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380624 | 1.00 | OPRM1 (0.64) | OPRM1OPRL1GRM5TP53GABRA1 | |
| SCHEMBL1929418 | 0.80 | OPRM1 (0.43) | OPRM1OPRL1 | |
| SCHEMBL1928271 | 0.78 | OPRM1 (0.39) | OPRM1OPRL1GABRA1GABRG2GABRB3 | |
| SCHEMBL1929168 | 0.74 | OPRM1 (0.38) | OPRM1OPRL1GRM5PLG | |
| SCHEMBL13380553 | 0.73 | OPRM1 (0.57) | OPRM1OPRL1TP53 | |
| SCHEMBL13380625 | 0.73 | OPRM1 (0.57) | OPRM1OPRL1TP53 | |
| SCHEMBL1930456 | 0.71 | OPRM1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL3409090 | 0.70 | OPRM1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL24832943 | 0.70 | OPRM1 (0.50) | OPRM1OPRL1GRM5TP53 | |
| SCHEMBL7396930 | 0.69 | OPRM1 (0.44) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172468-A1 | Benzimidazolone compounds | EURO-CELTIQUE S.A. (LU) | 2010-04-07 | — | — | EP | disclosed |
| EP-1975164-B1 | Octahydrobenzimidazolone compounds as analgetics | EURO CELTIQUE SA (LU) | 2010-01-27 | — | — | EP | disclosed |
| EP-1975164-A2 | Octahydrobenzimidazolone compounds as analgetics | EURO-CELTIQUE S.A. (LU) | 2008-10-01 | — | — | EP | disclosed |
| EP-1385518-B1 | BENZIMIDAZOLONE COMPOUNDS | EURO CELTIQUE SA (LU) | 2008-08-06 | — | — | EP | disclosed |