Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140497 | 0.85 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL3140507 | 0.85 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL13380589 | 0.85 | NR3C1 (0.58) | NR3C1 | |
| SCHEMBL13624508 | 0.76 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL3144678 | 0.75 | NR3C1 (0.66) | NR3C1PGR | |
| SCHEMBL3144688 | 0.75 | NR3C1 (0.66) | NR3C1PGR | |
| SCHEMBL13380581 | 0.74 | NR3C1 (0.52) | NR3C1FGFR1PGR | |
| SCHEMBL13380586 | 0.72 | NR3C1 (0.51) | NR3C1FGFR1PGR | |
| SCHEMBL13380583 | 0.72 | NR3C1 (0.48) | NR3C1FGFR1PGR | |
| SCHEMBL3144252 | 0.71 | NR3C1 (0.61) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100080786-A1 | Phenyl or Pyridinyl Substituted Indazoles Derivatives | ASTRAZENECA AB (SE) | 2010-04-01 | — | — | US | disclosed |
| US-20100080786-A1 | Phenyl or Pyridinyl Substituted Indazoles Derivatives | ASTRAZENECA AB (SE) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100080786-A1 | Phenyl or Pyridinyl Substituted Indazoles Derivatives | CYP3A5, CYP3A43, ABCB1 | NR3C1 2328/4885FGFR1 2844/4885PGR 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.