SCHEMBL13380896

SCHEMBL13380896

COCCN1C(=CC=C2CCC(C=CC3=[N+](CCOC)c4ccccc4C3(C)C)=C2Cl)C(C)(C)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 6/20 0.47
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
USP2 O75604 1/20 0.43
S1PR2 O95136 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
ALPG P10696 1/20 0.43
THRB P10828 1/20 0.43
PKM P14618 1/20 0.43
XBP1 P17861 1/20 0.43
CRHBP P24387 1/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
RAB9A P51151 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
CRHR2 Q13324 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13898090 0.96 PRMT1 (0.47) PRMT1MAPTMEN1NPC1USP2
SCHEMBL12040010 0.96 PRMT1 (0.47) PRMT1MAPTMEN1NPC1USP2
SCHEMBL14272568 0.96 PRMT1 (0.47) PRMT1MAPTMEN1NPC1USP2
SCHEMBL12857439 0.96 PRMT1 (0.47) PRMT1MAPTMEN1NPC1USP2
SCHEMBL24832449 0.91 PRMT1 (0.48) PRMT1MAPTMEN1NPC1USP2
SCHEMBL17340678 0.88 PRMT1 (0.45) PRMT1MAPTMEN1NPC1USP2
SCHEMBL859682 0.88 PRMT1 (0.43) PRMT1MAPTMEN1NPC1USP2
SCHEMBL12932098 0.88 PRMT1 (0.49) PRMT1MAPTMEN1NPC1USP2
SCHEMBL23320219 0.88 PRMT1 (0.47) PRMT1MAPTMEN1NPC1USP2
SCHEMBL7604098 0.87 PRMT1 (0.49) PRMT1MAPTMEN1NPC1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632953-B2 Process for making lithographic printing plate FUJIFILM CORPORATION (JP) 2014-01-21 US disclosed
US-20100081090-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7303857-B2 Photosensitive composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed