SCHEMBL859682

SCHEMBL859682

COCCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CCOC)c4ccc(C)cc4C3(C)C)=C2Cl)C(C)(C)c2cc(C)ccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 7/20 0.43
PRMT5 O14744 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
PTPN1 P18031 1/20 0.38
FOLH1 Q04609 1/20 0.34
HTR1A P08908 1/20 0.34
APP P05067 1/20 0.33
FOLR1 P15328 4/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
S1PR2 O95136 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
ALPG P10696 1/20 0.31
THRB P10828 1/20 0.31
PKM P14618 1/20 0.31
XBP1 P17861 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12155001 0.92 PRMT1 (0.47) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL14573277 0.91 PRMT1 (0.40) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL26207782 0.90 FOLH1 (0.44) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL26207804 0.90 FOLH1 (0.41) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL14272549 0.89 PRMT1 (0.50) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL13222312 0.89 PRMT1 (0.50) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL20381943 0.89 PRMT1 (0.47) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL13380896 0.88 PRMT1 (0.47) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL13813730 0.88 PRMT1 (0.42) PRMT1PRMT5CARM1PRMT8PTPN1
SCHEMBL13908160 0.88 PRMT1 (0.42) PRMT1PRMT5CARM1PRMT8PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
EP-2100731-A2 Lithographic printing plate precursor and method of lithographic printing Fujifilm Corporation (JP) 2009-09-16 EP disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed