Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381695 | 0.93 | L3MBTL1 (0.50) | ALDH1A1GAATSHRL3MBTL1 | |
| SCHEMBL13381541 | 0.86 | TSHR (0.44) | ALDH1A1GAATSHRL3MBTL1 | |
| SCHEMBL13381938 | 0.86 | TSHR (0.47) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2847041 | 0.85 | TP53 (0.55) | — | |
| SCHEMBL2837131 | 0.84 | L3MBTL1 (0.56) | ALDH1A1GAATSHRL3MBTL1 | |
| SCHEMBL13381614 | 0.84 | MAPT (0.49) | ALDH1A1GAATSHRL3MBTL1 | |
| SCHEMBL13381621 | 0.84 | TSHR (0.58) | ALDH1A1TSHR | |
| SCHEMBL13381969 | 0.84 | L3MBTL1 (0.48) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL13381505 | 0.83 | TSHR (0.60) | ALDH1A1TSHR | |
| SCHEMBL13381622 | 0.83 | GAA (0.52) | ALDH1A1GAATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |