SCHEMBL1338261

SCHEMBL1338261

CN(C)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26492812 0.77
SCHEMBL90602 0.75
SCHEMBL19170268 0.74
SCHEMBL3213660 0.72
SCHEMBL9587611 0.70 LMNA (0.30)
SCHEMBL10810982 0.70
SCHEMBL22577719 0.69
SCHEMBL9588359 0.68
SCHEMBL9589969 0.68
SCHEMBL11199350 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210040043-A1 HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS SOLVAY (BE) 2021-02-11 US disclosed
US-10829456-B2 Halogen substituted diketones, pyrazole compounds and processes for the manufacture of pyrazole compounds SOLVAY SA (BE) 2020-11-10 US disclosed
US-20190031616-A1 HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS SOLVAY SA (BE) 2019-01-31 US disclosed
EP-3408259-A1 HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS Solvay SA (BE) 2018-12-05 EP disclosed
WO-2017129759-A1 HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS SOLVAY SA (BE) 2017-08-03 WO disclosed
US-8063205-B2 Method for producing 2-oxazoline analogue or 1,3-oxazine analogue NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2011-11-22 US disclosed
US-20090281309-A1 METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-11-12 US disclosed
EP-1956012-A1 METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE National University Corporation Hokkaido University (JP) 2008-08-13 EP disclosed
US-7307185-B2 Process for producing optically active fluorochemical MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-12-11 US disclosed
US-20070191631-A1 Process for producing optically active fluorochemical MITSUBISHI GAS CHEMICAL COMPANY (JP) 2007-08-16 US disclosed
EP-1721885-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROCHEMICAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-11-15 EP disclosed