Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12428369 | 0.90 | HTR6 (1.00) | HTR6 | |
| SCHEMBL12428395 | 0.89 | HTR6 (0.86) | HTR6 | |
| SCHEMBL12428373 | 0.89 | HTR6 (1.00) | HTR6 | |
| SCHEMBL19381997 | 0.88 | HTR6 (0.80) | HTR6 | |
| SCHEMBL12427359 | 0.88 | HTR6 (0.78) | HTR6 | |
| SCHEMBL12427516 | 0.87 | HTR6 (0.83) | HTR6 | |
| SCHEMBL12427517 | 0.85 | HTR6 (0.69) | HTR6 | |
| SCHEMBL12427161 | 0.85 | HTR6 (0.73) | HTR6 | |
| SCHEMBL19382009 | 0.84 | HTR6 (0.77) | HTR6 | |
| SCHEMBL12441567 | 0.80 | HTR6 (1.00) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010041983-A1 | SUBSTITUTED 3-ARYLSULFONYL-PYRAZOLO[1,5-A]PYRIMIDINES, SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS AND METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ, ЛЛС (US) | 2010-04-15 | — | — | WO | disclosed |