Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384714 | 0.86 | ALDH1A1 (0.48) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384712 | 0.84 | ALDH1A1 (0.39) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384728 | 0.84 | ALDH1A1 (0.40) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384706 | 0.84 | ALDH1A1 (0.40) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384715 | 0.84 | ALDH1A1 (0.42) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384736 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384727 | 0.81 | HTT (0.51) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL13384703 | 0.81 | HTT (0.51) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL13384711 | 0.81 | ALDH1A1 (0.38) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL13384738 | 0.81 | KAT2B (0.46) | ALDH1A1POLBHTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087649-A1 | QUINOLINONE DERIVATIVES | TIBOTEC BVBA (BE) | 2010-04-08 | — | — | US | disclosed |
| WO-2008037784-A1 | QUINOLINONE DERIVATIVES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087649-A1 | QUINOLINONE DERIVATIVES | CHRM1, CYP2C8, CCR8 | ALDH1A1 784/4885POLB 3018/4885HTT 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.