Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.55 |
| ▸ | MMP3 | P08254 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384909 | 1.00 | MMP2 (0.55) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL9715636 | 0.96 | MAPT (0.50) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL11654970 | 0.96 | MAPT (0.50) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL3275036 | 0.91 | MMP2 (0.54) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL3275041 | 0.91 | MMP2 (0.54) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL13867952 | 0.88 | MAPT (0.49) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL20594637 | 0.88 | TP53 (0.47) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL21096319 | 0.88 | TP53 (0.47) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL8955714 | 0.88 | TP53 (0.47) | MMP2MMP3MAPTLMNATP53 | |
| SCHEMBL25907978 | 0.88 | TP53 (0.47) | MMP2MMP3MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8562863-B2 | Cholesteric glassy liquid crystals with hybrid chiral-nematic mesogens | THE UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | disclosed |
| US-20100086704-A1 | CHOLESTERIC GLASSY LIQUID CRYSTALS WITH HYBRID CHIRAL-NEMATIC MESOGENS | THE UNIVERSITY OF ROCHESTER | 2010-04-08 | — | — | US | disclosed |