Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385708 | 0.89 | PDPK1 (0.59) | PDPK1CYP2C9CYP2C19PTPN1GSK3B | |
| SCHEMBL13385524 | 0.85 | POLB (0.47) | PDPK1POLBALDH1A1LMNAHSP90AA1 | |
| SCHEMBL13385550 | 0.84 | CYP2C9 (0.62) | PDPK1POLBALDH1A1LMNAHSP90AA1 | |
| SCHEMBL657017 | 0.84 | GABBR2 (0.52) | PDPK1POLBUTS2RLMNATHRB | |
| SCHEMBL13385520 | 0.78 | POLB (0.52) | PDPK1POLBUTS2RALDH1A1LMNA | |
| SCHEMBL657567 | 0.76 | PDPK1 (0.78) | PDPK1POLBUTS2RALDH1A1LMNA | |
| SCHEMBL19320567 | 0.75 | CYP1A2 (0.45) | LMNAMAPTTHRBCYP2C9CYP2C19 | |
| SCHEMBL12174638 | 0.73 | PDPK1 (0.57) | PDPK1POLBNPSR1CYP2C9CYP2C19 | |
| SCHEMBL28818751 | 0.73 | PDPK1 (0.57) | PDPK1POLBNPSR1CYP2C9CYP2C19 | |
| SCHEMBL28818750 | 0.73 | PDPK1 (0.57) | PDPK1POLBNPSR1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |