Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 4/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657084 | 0.91 | PDPK1 (0.68) | PDPK1PARP10ERCC5FEN1SMN1; SMN2 | |
| SCHEMBL658086 | 0.85 | NPC1 (0.54) | PDPK1PARP10ERCC5FEN1SMN1; SMN2 | |
| SCHEMBL657803 | 0.82 | PDPK1 (0.47) | PDPK1PARP10ERCC5FEN1SMN1; SMN2 | |
| SCHEMBL657370 | 0.79 | L3MBTL1 (0.60) | ERCC5FEN1SRD5A2MMP1L3MBTL1 | |
| SCHEMBL2140616 | 0.78 | PDPK1 (0.67) | PDPK1SMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14518791 | 0.78 | ERCC5 (0.58) | PARP10ERCC5FEN1SMN1; SMN2SRD5A2 | |
| SCHEMBL24209329 | 0.76 | ERCC5 (0.70) | PARP10ERCC5FEN1SMN1; SMN2SRD5A2 | |
| SCHEMBL2141566 | 0.75 | PDPK1 (0.78) | PDPK1SMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11021138 | 0.75 | ERCC5 (0.55) | PARP10ERCC5FEN1SMN1; SMN2SRD5A2 | |
| SCHEMBL11764935 | 0.75 | ERCC5 (0.55) | PARP10ERCC5FEN1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |