Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 15/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.37 |
| ▸ | MTOR | P42345 | 10/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386250 | 1.00 | MAPT (0.38) | MAPTMEN1KMT2ANPC1PKM | |
| SCHEMBL13737559 | 1.00 | MAPT (0.38) | MAPTMEN1KMT2ANPC1PKM | |
| SCHEMBL13386209 | 0.91 | MAPT (0.35) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13386412 | 0.91 | MAPT (0.35) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL15925819 | 0.88 | MAPT (0.45) | MAPTMEN1KMT2ANPC1PKM | |
| SCHEMBL13386335 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2ANPC1PKM | |
| SCHEMBL15925818 | 0.83 | MAPT (0.42) | MAPTMEN1KMT2ANPC1PKM | |
| SCHEMBL17896427 | 0.83 | MAPT (0.42) | MAPTMEN1KMT2ANPC1PKM | |
| SCHEMBL15875885 | 0.83 | MAPT (0.33) | MAPTKMT2APKMALDH1A1HTT | |
| SCHEMBL15875833 | 0.83 | MAPT (0.33) | MAPTKMT2APKMALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828986-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-09-09 | — | — | US | claimed |
| EP-2699241-B1 | ANTIVIRAL COMPOUNDS | PROSETTA ANTIVIRAL INC (US) | 2016-07-27 | — | — | EP | disclosed |
| US-8828986-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120270854-A1 | Antiviral Compounds | PROSETTA ANTIVIRAL INC. (US) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270854-A1 | Antiviral Compounds | HAVCR2, MAVS, EIF2AK2 | MAPT 1569/4885MEN1 4541/4885KMT2A 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.