SCHEMBL133953

SCHEMBL133953

CC(CO)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4CCCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHA2 P29317 3/20 0.68
GPBAR1 Q8TDU6 3/20 0.68
HSD17B10 Q99714 3/20 0.68
TDP1 Q9NUW8 3/20 0.68
AKR1B10 O60218 2/20 0.68
AKR1B1 P15121 2/20 0.68
EFNA1 P20827 1/20 0.68
PSEN1 P49768 1/20 0.68
PSEN2 P49810 1/20 0.68
APH1B Q8WW43 1/20 0.68
NCSTN Q92542 1/20 0.68
APH1A Q96BI3 1/20 0.68
PSENEN Q9NZ42 1/20 0.68
MEN1 O00255 1/20 0.68
LMNA P02545 1/20 0.68
KMT2A Q03164 1/20 0.68
CYP2D6 P10635 1/20 0.57
CYP2C19 P33261 1/20 0.57
INPP5D Q92835 1/20 0.56
OSBP P22059 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3447578 1.00 EPHA2 (0.68) EPHA2GPBAR1HSD17B10TDP1AKR1B10
SCHEMBL28093234 1.00 EPHA2 (0.68) EPHA2GPBAR1HSD17B10TDP1AKR1B10
SCHEMBL17912309 1.00 EPHA2 (0.68) EPHA2GPBAR1HSD17B10TDP1AKR1B10
SCHEMBL30575186 1.00 EPHA2 (0.68) EPHA2GPBAR1HSD17B10TDP1AKR1B10
Water SCHEMBL4949880 0.99 EPHA2 (0.67) EPHA2GPBAR1HSD17B10TDP1AKR1B10
Methoxymethane SCHEMBL4737657 0.97 GPBAR1 (0.64) EPHA2GPBAR1HSD17B10TDP1AKR1B10
SCHEMBL4735796 0.95 GPBAR1 (0.62) EPHA2GPBAR1HSD17B10TDP1AKR1B10
Ether SCHEMBL4735230 0.94 EPHA2 (0.61) EPHA2GPBAR1HSD17B10TDP1AKR1B10
SCHEMBL4735219 0.93 EPHA2 (0.60) EPHA2GPBAR1HSD17B10TDP1AKR1B10
SCHEMBL4735773 0.93 EPHA2 (0.60) EPHA2GPBAR1HSD17B10TDP1AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6248 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410758-B1 None US claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
EP-4743437-A1 DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-05-20 EP claimed
CN-122059896-A Ionizable lipid gene vector and organ selective regulation method 南开大学 2026-05-19 CN claimed
CN-118141102-B Compound natural antioxidant, compound grease, antioxidant preparation and application thereof 江苏瀚康生物科技有限公司 2026-05-15 CN claimed
EP-4739687-A1 STABLE PALIPERIDONE PALMITATE COMPOSITION USING THERMAL TREATMENT Eugia Pharma Specialities Limited (IN) 2026-05-13 EP claimed
EP-4731258-A1 LIPID NANOPARTICLES CONTAINING DISULFIDE LIPIDS AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-04-29 EP claimed
EP-4554981-B1 SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY CENTRO ALTA TECNOLOGIA ST DI RICERCHE CHIMICHE E BIOCHIMICHE G RONZONI S R L (IT) 2026-04-22 EP claimed
EP-4721759-A1 LIPID NANOPARTICLE FOR DELIVERING NUCLEIC ACID DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF Cansino (Shanghai) Biological Research Co., Ltd. (CN) 2026-04-08 EP claimed
EP-4707289-A1 STEROID-CATIONIC LIPID COMPOUND AND USE THEREOF Cansino (Shanghai) Biological Research Co., Ltd. (CN) 2026-03-11 EP claimed
US-4707453-A Vesicle including a metal marker for use in an assay BECTON DICKINSON AND COMPANY (US) 1987-11-17 US claimed
US-4619795-A Method for preparing lipid vesicles TECHNICON INSTRUMENTS CORP. (US) 1986-10-28 US claimed
EP-0186352-A2 Preparation of lipid vesicles Bayer Corporation (US) 1986-07-02 EP claimed
EP-0063678-B1 PROCESS FOR THE PREPARATION OF CHOLESTEROL DERIVATIVES, AND INTERMEDIATE DERIVATIVES THEREFOR F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-08-21 EP claimed
US-4400295-A REACTION PRODUCT OF A FATTY ACID, AMINO ACID AND A SECONDARY COMPOUND LOIRE COSMETICS CO., LTD. (JP) 1983-08-23 US claimed
EP-0063678-A2 Process for the preparation of cholesterol derivatives, and intermediate derivatives therefor F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-11-03 EP claimed
US-4224319-A AMINO ACID, TRIGLYCERIDE, VITAMINS A AND E MARCADET ERNEST 1980-09-23 US claimed
US-4193983-A Labeled liposome particle compositions and immunoassays therewith SYVA COMPANY (US) 1980-03-18 US claimed
US-4008127-A Process for the preparation of cholesterol oxidase BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-02-15 US claimed
US-3974188-A PHOSPHATE THE LION DENTIFRICE CO., LTD. (JA) 1976-08-10 US claimed