Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.64 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.64 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.64 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.64 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.64 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.64 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.64 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447578 | 0.97 | EPHA2 (0.68) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL17912309 | 0.97 | EPHA2 (0.68) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL30575186 | 0.97 | EPHA2 (0.68) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL133953 | 0.97 | EPHA2 (0.68) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL28093234 | 0.97 | EPHA2 (0.68) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| Water SCHEMBL4949880 | 0.96 | EPHA2 (0.67) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL4735796 | 0.94 | GPBAR1 (0.62) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| Ether SCHEMBL4735230 | 0.93 | EPHA2 (0.61) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL4735219 | 0.92 | EPHA2 (0.60) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 | |
| SCHEMBL4735773 | 0.92 | EPHA2 (0.60) | GPBAR1EPHA2HSD17B10AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |