Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123922 | 0.92 | TSHR (0.55) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9907091 | 0.90 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16576778 | 0.90 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL329256 | 0.89 | TSHR (0.55) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL27474024 | 0.86 | TSHR (0.49) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL12808627 | 0.85 | SMN1; SMN2 (0.47) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9914884 | 0.83 | — | — | |
| SCHEMBL21516451 | 0.83 | SMN1; SMN2 (0.49) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL12158351 | 0.83 | TSHR (0.55) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL26661587 | 0.83 | SMN1; SMN2 (0.51) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9921477-B2 | Photoactivable nitrogen bases | BASE SE (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20100105794-A1 | PHOTOACTIVABLE NITROGEN BASES | CIBA CORPORATION (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, NR0B1, NR0B2 | TSHR 801/4885MAPK1 1258/4885SMN1; SMN2 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.