Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 10/20 | 0.50 |
| ▸ | DRD2 | P14416 | 8/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | HTR2C | P28335 | 8/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13398809 | 0.95 | SLC6A4 (0.47) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13398688 | 0.91 | SLC6A4 (0.56) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13399517 | 0.90 | SLC6A4 (0.48) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13398758 | 0.89 | DRD3 (0.62) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13399321 | 0.85 | SLC6A4 (0.57) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13399292 | 0.85 | DRD2 (0.49) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13398761 | 0.85 | HTR2A (0.57) | SLC6A4DRD3HTR2AHTR2CKCNH2 | |
| SCHEMBL13398990 | 0.85 | DRD3 (0.50) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13399489 | 0.84 | SLC6A4 (0.61) | SLC6A4SLC6A2DRD3DRD2DRD4 | |
| SCHEMBL13399510 | 0.84 | SLC6A4 (0.59) | SLC6A4SLC6A2DRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038948-A2 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2010-04-08 | — | — | WO | disclosed |