SCHEMBL133996

SCHEMBL133996

O=[N+]([O-])c1cc(S(=O)(=O)c2ccc(F)c([N+](=O)[O-])c2)ccc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 2/20 1.00
ALDH1A1 P00352 3/20 0.60
HIF1A Q16665 1/20 0.60
GAA P10253 4/20 0.59
LMNA P02545 3/20 0.59
HTT P42858 3/20 0.59
MAPT P10636 3/20 0.59
NPSR1 Q6W5P4 2/20 0.59
MITF O75030 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.50
MAPK1 P28482 1/20 0.50
KMT2A Q03164 5/20 0.48
MEN1 O00255 3/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA1 P00915 4/20 0.46
CA12 O43570 3/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510874 1.00 VCAM1 (1.00) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL6417727 1.00 VCAM1 (1.00) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL27898111 0.91 VCAM1 (0.83) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL14228439 0.90 VCAM1 (0.81) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL17245004 0.90 VCAM1 (0.81) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL17245003 0.90 VCAM1 (0.81) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL8761704 0.87 VCAM1 (0.76) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL7534749 0.86 VCAM1 (0.73) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL14956676 0.85 VCAM1 (0.74) VCAM1ALDH1A1HIF1AGAALMNA
SCHEMBL377111 0.85 VCAM1 (0.73) VCAM1ALDH1A1HIF1AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165350-A Process for preparing wear-resistant rubber sole material by supercritical foaming method 广东海瑞斯新材料股份有限公司 2024-06-11 CN claimed
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US claimed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US claimed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US claimed
EP-0688429-B1 MACROMOLECULAR MICROPARTICLES AND METHODS OF PRODUCTION EPIC THERAPEUTICS INC (US) 1998-02-11 EP claimed
US-5401634-A Stable biologically active fluorochemical emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-28 US claimed
EP-0216272-B1 IMMOBILIZATION OF BIOCATALYSTS ON GRANULAR DIATOMACEOUS EARTH HAARMANN & REIMER CORP. (US) 1993-05-26 EP claimed
EP-0234415-B1 METHOD FOR THE PREPARATION OF AN ENZYME-CONTAINING CELL IMMOBILIZED CONJUGATE AND THE IMMOBILIZED CONJUGATE PRODUCED THEREBY HAARMANN & REIMER CORP. (US) 1991-07-10 EP claimed
EP-0214330-B1 METHOD FOR IMMOBILIZING SUBSTANCES IN SYNTHETIC SOLID PHASES, AND SYNTHETIC SOLID PHASES FOR USE IN IMMUNOSORBENT ASSAYS PROGEN Biotechnik GmbH (DE) 1989-04-26 EP claimed
US-4757008-A Enzyme immobilization in a macroporous non-ionic resin MILES INC. (US) 1988-07-12 US claimed
EP-0216272-A2 Immobilization of biocatalysts on granular diatomaceous earth HAARMANN & REIMER CORP. (US) 1987-04-01 EP claimed
EP-0184710-A2 Magnetic microspheres BAYER AG (DE) 1986-06-18 EP claimed
EP-0043675-B1 MODIFIED HEMOGLOBINS SUITABLE FOR USE AS OXYGEN CARRIERS FOR BLOOD SUBSTITUTES AJINOMOTO CO., INC. (JP) 1984-10-03 EP claimed
EP-0104571-A2 Immobilization of biocatalysts on granular carbon MILES INC. (US) 1984-04-04 EP claimed
US-4438196-A POLYAMINES MILES LABORATORIES, INC. (US) 1984-03-20 US claimed
US-4377512-A ESTERIFICATION INULIN AND REACTING WITH HEMOGLOBIN AJINOMOTO CO., INC. (JP) 1983-03-22 US claimed
EP-0043675-A1 Modified hemoglobins suitable for use as oxygen carriers for blood substitutes AJINOMOTO CO., INC. (JP) 1982-01-13 EP claimed
US-4071321-A Test composition and device for determining peroxidatively active substances MILES LABORATORIES, INC. (US) 1978-01-31 US claimed
US-4071317-A Test composition and device for determining peroxidatively active substances and process for preparing same MILES LABORATORIES, INC. (US) 1978-01-31 US claimed
US-4002532-A BINDING ANTIBODIES WELTMAN JOEL K 1977-01-11 US claimed