Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405771 | 1.00 | GAA (0.55) | GAAALOX5CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL21635117 | 0.81 | MTOR (0.50) | GAATSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1331551 | 0.78 | TDP1 (0.56) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1330911 | 0.78 | TDP1 (0.56) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1531678 | 0.78 | TDP1 (0.56) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL33928 | 0.78 | TDP1 (0.56) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL33927 | 0.78 | TDP1 (0.56) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28705330 | 0.77 | KMT2A (0.50) | GAASMN1; SMN2ALDH1A1MAPTMEN1 | |
| Methane SCHEMBL6442579 | 0.77 | TDP1 (0.54) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10424136 | 0.77 | TDP1 (0.54) | GAACYP3A4TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062899-B1 | Identification and quantitative determination of major chemical contaminants associated with L-Tryptophan | NHK Laboratories, Inc. (US) | 2011-11-22 | — | — | US | claimed |
| US-8062899-B1 | Identification and quantitative determination of major chemical contaminants associated with L-Tryptophan | NHK Laboratories, Inc. (US) | 2011-11-22 | — | — | US | disclosed |