Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 5/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12215326 | 0.87 | APP (0.40) | MAPTSMN1; SMN2KDM4ELMNATP53 | |
| SCHEMBL13400575 | 0.87 | APP (0.35) | LMNAMETIGF1RALOX15ALOX5 | |
| SCHEMBL13839012 | 0.84 | APP (0.41) | SMN1; SMN2ALOX5APPYWHAGPOLB | |
| SCHEMBL13400581 | 0.83 | RIPK1 (0.33) | METALOX5APPYWHAGPOLB | |
| SCHEMBL13400579 | 0.82 | SLC7A5 (0.32) | APPYWHAGPOLBAPEX1HTT | |
| SCHEMBL813463 | 0.81 | APP (0.38) | ALOX5APPPOLBAPEX1HTT | |
| SCHEMBL13159307 | 0.81 | APP (0.38) | ALOX5APPPOLBAPEX1HTT | |
| SCHEMBL13159274 | 0.80 | POLB (0.37) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL813113 | 0.80 | POLB (0.37) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL13400580 | 0.80 | TSHR (0.37) | CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100103352-A1 | OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER | KONICA MINOLTA OPTO, INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100103352-A1 | OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER | KONICA MINOLTA OPTO, INC. (JP) | 2010-04-29 | — | — | US | disclosed |