Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000355 | 0.80 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18571426 | 0.74 | HDAC1 (0.51) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18571638 | 0.74 | HDAC1 (0.51) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL20669088 | 0.74 | HDAC1 (0.51) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL20835055 | 0.70 | HDAC1 (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22507711 | 0.64 | — | — | |
| SCHEMBL18792990 | 0.64 | — | — | |
| SCHEMBL23862923 | 0.64 | — | — | |
| SCHEMBL24705819 | 0.62 | — | — | |
| SCHEMBL9804119 | 0.61 | SMN1; SMN2 (0.52) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691826-B2 | Polysialic acid having a moiety linked at one or each terminal unit of a functional group of from N-maleimido, vinysulphone, N-iodoacetamide, and orthopyridyl disulphide; conjugation with protein or peptide having a cysteine to attach to the thiol;bioavailability; drug delivery | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2010-04-06 | — | — | US | disclosed |