Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592017 | 0.91 | SIGMAR1 (0.54) | EPHX1EPHX2SIGMAR1 | |
| SCHEMBL18571426 | 0.86 | HDAC1 (0.51) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL25563633 | 0.86 | HDAC1 (0.51) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL18571638 | 0.86 | HDAC1 (0.51) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL20669088 | 0.86 | HDAC1 (0.51) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL15189278 | 0.76 | EPHX1 (0.46) | SMN1; SMN2EPHX1ALDH1A1EPHX2CYP3A4 | |
| SCHEMBL3068845 | 0.74 | SIGMAR1 (0.44) | SMN1; SMN2EPHX1ALDH1A1EPHX2CYP3A4 | |
| SCHEMBL38658755 | 0.74 | SMN1; SMN2 (0.91) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL15000355 | 0.74 | HDAC1 (0.44) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL22860279 | 0.73 | EPHX1 (0.42) | SMN1; SMN2EPHX1ALDH1A1EPHX2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153616-B1 | HEAT-SENSITIVE RECORDING MATERIALS | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0153616-A2 | Heat-sensitive recording materials | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-04 | — | — | EP | disclosed |