Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559511 | 0.77 | SMN1; SMN2 (0.43) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL530122 | 0.76 | ALDH1A1 (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL21795691 | 0.74 | SMN1; SMN2 (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9066356 | 0.73 | TSHR (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL12065003 | 0.73 | ALDH1A1 (0.40) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21468732 | 0.71 | ALDH1A1 (0.33) | TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1458135 | 0.71 | ALDH1A1 (0.33) | TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28405766 | 0.71 | TSHR (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL3227018 | 0.71 | ALDH1A1 (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4740030 | 0.71 | ALDH1A1 (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087618-A1 | Linear (meth)acryloyl-containing compound, star (meth) acryloyl- containing compound, and method of manufacture | DIC CORPORATION (JP) | 2010-04-08 | — | — | US | disclosed |