Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 4/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260296 | 0.92 | MAOA (0.62) | MAOAMAOBTHRBTHRASLC2A1 | |
| SCHEMBL5170523 | 0.92 | MAOA (0.52) | MAOAMAOBTHRBTHRASLC2A1 | |
| SCHEMBL10528256 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10528290 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10528218 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10525929 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10525833 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10527847 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10527721 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 | |
| SCHEMBL10534710 | 0.90 | MAOA (0.46) | MAOAMAOBTHRBTHRAPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |