Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311577 | 0.86 | RARB (0.39) | CYP2D6CYP3A4RARBCYP19A1CYP2C9 | |
| SCHEMBL13402119 | 0.83 | KDM4E (0.38) | KDM4EMEN1KMT2ADRD2DRD4 | |
| SCHEMBL13401931 | 0.82 | NR5A1 (0.45) | NR5A1 | |
| SCHEMBL9346140 | 0.80 | CYP2D6 (0.54) | CYP2D6CYP3A4RARBKDM4ECYP19A1 | |
| SCHEMBL9346152 | 0.80 | CYP2D6 (0.54) | CYP2D6CYP3A4RARBKDM4ECYP19A1 | |
| SCHEMBL10486154 | 0.80 | CYP1A2 (0.45) | CYP1A2 | |
| SCHEMBL10486152 | 0.80 | CYP1A2 (0.45) | CYP1A2 | |
| SCHEMBL10707658 | 0.80 | CYP1A2 (0.45) | CYP1A2 | |
| SCHEMBL20888411 | 0.80 | KDM4E (0.39) | CYP2D6CYP3A4RARBKDM4EMEN1 | |
| SCHEMBL10486180 | 0.79 | CYP1A2 (0.44) | CYP2D6CYP2C9CYP2C19CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |