Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402113 | 0.86 | CYP2D6 (0.40) | RARBCYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL10311456 | 0.83 | NR5A1 (0.38) | RARBLTA4H | |
| SCHEMBL10311584 | 0.82 | RARB (0.42) | RARBRARAITGB3ITGA2B | |
| SCHEMBL10311471 | 0.81 | TP53 (0.33) | RARBLTA4HNPC1RAB9A | |
| SCHEMBL13401931 | 0.78 | NR5A1 (0.45) | LTA4HITGB3ITGA2BITGAVCHRM2 | |
| SCHEMBL10311524 | 0.77 | HRH3 (0.37) | CYP3A4CYP2C9RAB9AHRH3 | |
| SCHEMBL9346140 | 0.77 | CYP2D6 (0.54) | RARBCYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL9346152 | 0.77 | CYP2D6 (0.54) | RARBCYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL10486154 | 0.77 | CYP1A2 (0.45) | CYP1A2HRH3LMNA | |
| SCHEMBL10707658 | 0.77 | CYP1A2 (0.45) | CYP1A2HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |