Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402130 | 0.97 | RARB (0.52) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL10311590 | 0.91 | RARB (0.48) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL10311573 | 0.89 | RARB (0.46) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL9842492 | 0.77 | RARB (0.47) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL9842642 | 0.76 | RARB (0.47) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL9842456 | 0.75 | RARB (0.48) | RARBRARARARGPTPN11MCL1 | |
| SCHEMBL13401932 | 0.75 | CRBN (0.46) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL9842572 | 0.75 | RARB (0.51) | RARBRARATSHRRARG | |
| SCHEMBL27296189 | 0.73 | TSHR (0.61) | RARBRARATSHRALDH1A1LMNA | |
| SCHEMBL13402072 | 0.73 | S1PR1 (0.45) | RARBRARAPTPN11MCL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |