Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 7/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842462 | 0.87 | PTPN11 (0.42) | RARBRARAPTPN11MCL1PPARD | |
| SCHEMBL9842253 | 0.83 | KDM4E (0.43) | RARBRARARARGPTPN11MCL1 | |
| SCHEMBL9842723 | 0.83 | TTR (0.44) | RARBRARARARGMCL1PPARD | |
| SCHEMBL9842489 | 0.79 | TTR (0.46) | RARBRARAMCL1CAMKK1CAMKK2 | |
| SCHEMBL9842460 | 0.79 | RARB (0.61) | RARBRARARARG | |
| SCHEMBL9842575 | 0.79 | RARB (0.61) | RARBRARARARG | |
| SCHEMBL9842396 | 0.78 | RARB (0.62) | RARBRARARARG | |
| SCHEMBL13402130 | 0.78 | RARB (0.52) | RARBRARARARGPTPN11MCL1 | |
| SCHEMBL13402114 | 0.75 | RARB (0.48) | RARBRARARARGPTPN11MCL1 | |
| SCHEMBL10311590 | 0.75 | RARB (0.48) | RARBRARARARGPTPN11MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |