SCHEMBL13402118

SCHEMBL13402118

Cc1ccc(CCC2CCC(c3ccc(OCCCCCCOc4ccc(C)cc4)c(F)c3)CC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.40
PPARA Q07869 2/20 0.40
KCNH2 Q12809 4/20 0.36
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
MAOB P27338 1/20 0.34
KDM4E B2RXH2 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
KDM1A O60341 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13402129 0.96 PPARG (0.40) PPARGPPARAALDH1A1LMNA
SCHEMBL10311583 0.93 PPARG (0.38) PPARGPPARAKCNH2ITGB3ITGA2B
SCHEMBL11056988 0.78 THRA (0.42) KDM1AMAPT
SCHEMBL11060222 0.78 THRA (0.42) KDM1AALDH1A1LMNAMAPT
SCHEMBL11066516 0.78 THRA (0.42) KDM1AMAPT
SCHEMBL11062490 0.78 THRA (0.42) KDM1AALDH1A1LMNAMAPT
SCHEMBL11063257 0.78 THRA (0.42) KDM1AALDH1A1LMNAMAPT
SCHEMBL11058882 0.78 THRA (0.42) KDM1A
SCHEMBL11062830 0.78 THRA (0.42) KDM1AMAPT
SCHEMBL11060243 0.78 THRA (0.42) KDM1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed