Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311584 | 0.90 | RARB (0.42) | RARBESR1HDAC3HDAC4HDAC1 | |
| SCHEMBL13402021 | 0.86 | KMT2A (0.48) | SMN1; SMN2KMT2AESR1PLA2G4BTP53 | |
| SCHEMBL13402155 | 0.84 | RARB (0.41) | RARBITGB3ITGA2BCNR2 | |
| SCHEMBL10540387 | 0.83 | RARB (0.64) | RARBSMN1; SMN2KMT2AESR1HDAC3 | |
| SCHEMBL9157429 | 0.81 | SMN1; SMN2 (0.44) | RARBSMN1; SMN2KMT2AESR1ITGB3 | |
| SCHEMBL11276110 | 0.79 | KMT2A (0.48) | SMN1; SMN2KMT2AESR1NPC1LMNA | |
| SCHEMBL11280516 | 0.79 | KMT2A (0.48) | SMN1; SMN2KMT2AESR1NPC1LMNA | |
| SCHEMBL11280797 | 0.79 | KMT2A (0.48) | SMN1; SMN2KMT2AESR1NPC1LMNA | |
| SCHEMBL11285774 | 0.79 | KMT2A (0.48) | SMN1; SMN2KMT2AESR1NPC1LMNA | |
| SCHEMBL11283806 | 0.79 | KMT2A (0.48) | SMN1; SMN2KMT2AESR1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |