Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311603 | 0.93 | RARB (0.40) | RARBRARAS1PR1RARGITGB3 | |
| SCHEMBL13402139 | 0.87 | S1PR1 (0.41) | RARBRARAS1PR1RARGITGB3 | |
| SCHEMBL13402131 | 0.84 | RARB (0.46) | RARBITGB3ITGA2BCNR2 | |
| SCHEMBL9479205 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 | |
| SCHEMBL9475902 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 | |
| SCHEMBL9476333 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 | |
| SCHEMBL9476687 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 | |
| SCHEMBL9479168 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 | |
| SCHEMBL9477118 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 | |
| SCHEMBL9652131 | 0.80 | THRA (0.51) | RARBRARAS1PR1PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |