Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | ACR | P10323 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21185914 | 0.95 | NPC1 (0.61) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11547482 | 0.94 | LMNA (0.67) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11548224 | 0.94 | LMNA (0.67) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11547986 | 0.94 | LMNA (0.67) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11551955 | 0.94 | MAPT (0.64) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11551224 | 0.94 | MAPT (0.64) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21185826 | 0.94 | NPC1 (0.62) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18635918 | 0.94 | NPC1 (0.62) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14097575 | 0.93 | NPC1 (0.67) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11549571 | 0.93 | NPC1 (0.67) | NPC1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |