Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000270 | 0.86 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL13310847 | 0.85 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10000268 | 0.85 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL19387236 | 0.85 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10502311 | 0.84 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8749061 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8748888 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8748813 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8748530 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8749126 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |