⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109 | 0.65 | — | — | |
| SCHEMBL449047 | 0.65 | — | — | |
| SCHEMBL451693 | 0.65 | — | — | |
| SCHEMBL8936 | 0.65 | — | — | |
| SCHEMBL5969912 | 0.64 | PI4KA (0.37) | — | |
| SCHEMBL4750497 | 0.63 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL8615 | 0.62 | — | — | |
| SCHEMBL29586296 | 0.62 | — | — | |
| SCHEMBL1488501 | 0.61 | — | — | |
| Bromide SCHEMBL21060510 | 0.61 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290434-A | Spiropiperidine derivative containing alpha-methylene-gamma-butyrolactone, preparation method and application thereof | 南开大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20240101546-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | EUBULUS BIOTHERAPEUTICS INC (CN) | 2024-03-28 | — | — | US | claimed |
| CN-114656462-B | N-containing heterocyclic aromatic hydrazone derivatives, and preparation method and application thereof | 南开大学 | 2023-12-19 | — | — | CN | claimed |
| CN-114656462-A | N-containing heterocyclic aromatic hydrazone derivatives, and preparation method and application thereof | 南开大学 | 2022-06-24 | — | — | CN | claimed |
| EP-3459951-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-11 | — | — | EP | claimed |
| US-20220055996-A1 | METHOD OF PREPARING MALONONITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2022-02-24 | — | — | US | claimed |
| EP-3822253-A1 | METHOD FOR PREPARING PROPANEDINITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-05-19 | — | — | EP | claimed |
| EP-3558969-A1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2019-10-30 | — | — | EP | claimed |
| WO-2018119036-A1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN BIOTECH, INC. (US) | 2018-06-28 | — | — | WO | claimed |
| US-20110263662-A1 | 1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-10-27 | — | — | US | claimed |
| WO-2011032656-A1 | 5-FLUOR-2-THIO-SUBSTITUTED PYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-03-24 | — | — | WO | claimed |
| EP-2252594-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2010-11-24 | — | — | EP | claimed |
| EP-2188282-A2 | 1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2010-05-26 | — | — | EP | claimed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | claimed |
| US-20090203647-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-08-13 | — | — | US | claimed |
| WO-2009094442-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-07-30 | — | — | WO | claimed |
| WO-2009022311-A2 | 1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-02-19 | — | — | WO | claimed |
| US-20080220286-A1 | Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films | TSINGHUA UNIVERSITY (CN) | 2008-09-11 | — | — | US | claimed |
| WO-1999037636-A1 | HETEROCYCLYL-DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 1999-07-29 | — | — | WO | claimed |