SCHEMBL13405652

SCHEMBL13405652

CC(=O)OCC(=O)Nc1ccc(NC(=O)c2ccc(C#N)o2)c(N2CCCCC2)c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14078172 0.87 CSF1R (0.77) CSF1R
SCHEMBL3536734 0.84 CSF1R (0.78) CSF1R
SCHEMBL13439366 0.84 CSF1R (0.75) CSF1R
SCHEMBL3537055 0.81 CSF1R (1.00) CSF1R
SCHEMBL13405653 0.79 CSF1R (0.68) CSF1R
SCHEMBL14078158 0.79 CSF1R (0.85) CSF1R
SCHEMBL14078166 0.79 CSF1R (1.00) CSF1R
SCHEMBL13148115 0.78 CSF1R (1.00) CSF1R
SCHEMBL13148110 0.78 CSF1R (0.78) CSF1R
SCHEMBL14078160 0.77 CSF1R (0.80) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705042-B2 Class of arylamide compounds useful as inhibitors of c-fms kinase JANSSEN PHARMACEUTICA NV (BE) 2010-04-27 — — US disclosed
US-7705042-B2 Class of arylamide compounds useful as inhibitors of c-fms kinase JANSSEN PHARMACEUTICA NV (BE) 2010-04-27 — — US disclosed
Send feedback