Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536734 | 0.91 | CSF1R (0.78) | CSF1R | |
| SCHEMBL13439366 | 0.88 | CSF1R (0.75) | CSF1R | |
| SCHEMBL3537055 | 0.87 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405652 | 0.87 | CSF1R (0.67) | CSF1R | |
| SCHEMBL13148110 | 0.84 | CSF1R (0.78) | CSF1R | |
| SCHEMBL13148115 | 0.84 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405653 | 0.84 | CSF1R (0.68) | CSF1R | |
| SCHEMBL14078160 | 0.83 | CSF1R (0.80) | CSF1R | |
| SCHEMBL14078158 | 0.83 | CSF1R (0.85) | CSF1R | |
| SCHEMBL14078171 | 0.83 | CSF1R (0.77) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427683-B2 | c-fms kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-23 | — | — | US | disclosed |
| US-7427683-B2 | c-fms kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-23 | — | — | US | disclosed |