Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 0.62 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.61 |
| ▸ | KIT | P10721 | 1/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405669 | 0.90 | CSF1R (0.62) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3536763 | 0.89 | CSF1R (0.67) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3964576 | 0.87 | CSF1R (0.48) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405658 | 0.86 | CSF1R (0.76) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405698 | 0.85 | CSF1R (0.61) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405699 | 0.85 | CSF1R (0.62) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405666 | 0.84 | CSF1R (0.59) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405680 | 0.84 | CSF1R (0.69) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL5388363 | 0.83 | CSF1R (0.62) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3542020 | 0.83 | CSF1R (0.58) | CSF1RNTRK1KITAXLFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |