Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 2/20 | 0.35 |
| ▸ | STK25 | O00506 | 2/20 | 0.35 |
| ▸ | RIOK3 | O14730 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | GAK | O14976 | 2/20 | 0.35 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.35 |
| ▸ | MUSK | O15146 | 2/20 | 0.35 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | MAP3K13 | O43283 | 2/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963254 | 0.91 | CSF1R (0.49) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405705 | 0.87 | CSF1R (0.62) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3966702 | 0.86 | CSF1R (0.51) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3970327 | 0.84 | CSF1R (0.51) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3970081 | 0.84 | CSF1R (0.48) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3961963 | 0.83 | CSF1R (0.46) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3969531 | 0.82 | CSF1R (0.46) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13405669 | 0.79 | CSF1R (0.62) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3970086 | 0.77 | CSF1R (0.75) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL3964080 | 0.77 | CSF1R (0.74) | CSF1RNTRK1KITAXLFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | claimed |