SCHEMBL13405752

SCHEMBL13405752

CC1CCN(c2nc(C3CCOCC3)ccc2NC(=O)c2ccc(C#N)o2)CC1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13405750 0.91 CSF1R (0.76) CSF1R
SCHEMBL3965761 0.86 CSF1R (0.51) CSF1R
SCHEMBL13405753 0.81 CSF1R (0.46) CSF1R
SCHEMBL13405733 0.81 CSF1R (1.00) CSF1R
SCHEMBL13405756 0.79 CSF1R (0.72) CSF1R
SCHEMBL13405754 0.79 CSF1R (0.72) CSF1R
SCHEMBL13767330 0.79 CSF1R (0.42) CSF1R
SCHEMBL3538933 0.78 CSF1R (0.78) CSF1R
SCHEMBL3961588 0.77 CSF1R (0.57) CSF1R
SCHEMBL3544978 0.77 CSF1R (0.79) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705042-B2 Class of arylamide compounds useful as inhibitors of c-fms kinase JANSSEN PHARMACEUTICA NV (BE) 2010-04-27 US disclosed
US-7705042-B2 Class of arylamide compounds useful as inhibitors of c-fms kinase JANSSEN PHARMACEUTICA NV (BE) 2010-04-27 US disclosed