Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405756 | 0.97 | CSF1R (0.72) | CSF1RKDM4EALDH1A1GAARECQL | |
| Trifluoroacetic Acid SCHEMBL3540848 | 0.92 | CSF1R (0.66) | CSF1RKDM4EALDH1A1GAA | |
| SCHEMBL3969432 | 0.88 | CSF1R (0.56) | CSF1RKDM4EALDH1A1GAARECQL | |
| SCHEMBL13767720 | 0.86 | CSF1R (0.56) | CSF1RKDM4EALDH1A1GAARECQL | |
| SCHEMBL13405733 | 0.84 | CSF1R (1.00) | CSF1R | |
| SCHEMBL3544978 | 0.79 | CSF1R (0.79) | CSF1R | |
| SCHEMBL13405752 | 0.79 | CSF1R (0.68) | CSF1R | |
| SCHEMBL3534730 | 0.77 | ALDH1A1 (0.50) | CSF1RKDM4EALDH1A1RECQL | |
| SCHEMBL5188971 | 0.75 | ALDH1A1 (0.55) | KDM4EALDH1A1GAARECQL | |
| SCHEMBL3537014 | 0.74 | MAPT (0.48) | KDM4EALDH1A1GAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |