Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798326 | 0.85 | GABRA1 (0.55) | TSHRGABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL10486191 | 0.84 | GABRA1 (0.59) | TSHRGABRA1GABRB2RORCGABRG2 | |
| SCHEMBL21419965 | 0.83 | TSHR (0.50) | TSHRGABRA1GABRB2RORCSLC6A2 | |
| SCHEMBL4779398 | 0.80 | GABRA1 (0.46) | TSHRGABRA1GABRB2GABRG2GABRB3 | |
| SCHEMBL202738 | 0.78 | TSHR (0.68) | TSHRGABRA1GABRB2RORCGABRG2 | |
| SCHEMBL561299 | 0.78 | TSHR (0.68) | TSHRGABRA1GABRB2RORCGABRG2 | |
| SCHEMBL560346 | 0.78 | TSHR (0.68) | TSHRGABRA1GABRB2RORCGABRG2 | |
| SCHEMBL560318 | 0.78 | TSHR (0.68) | TSHRGABRA1GABRB2RORCGABRG2 | |
| SCHEMBL6870041 | 0.78 | TSHR (0.53) | TSHRGABRA1GABRB2RORCGABRG2 | |
| SCHEMBL4912786 | 0.77 | TSHR (0.52) | TSHRGABRA1GABRB2RORCGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705191-B2 | Hydrofluoroalkyl phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080119566-A1 | Hydrofluoroalkyl phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-05-22 | — | — | US | disclosed |
| WO-2008008492-A2 | HYDROFLUOROALKYL PHENOLS HAVING ANESTHETIC PROPERTIES | UNIVERSITY OF IOWA RESEARCH FDTN. (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119566-A1 | Hydrofluoroalkyl phenols having anesthetic properties | OPRL1, VHL, PPARG | TSHR 2535/4885GABRA1 697/4885GABRB2 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.